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Expert Video - Why does AML treatment failure happen after chemo and/or radiation therapy?

Dr. Barry Skikne, an expert on acute myeloid leukemia (AML) at the University of Kansas Medical Center in Kansas City, describes how AML and leukemic cells may arise after treatment with chemotherapy and/or radiation therapy. He talks about prior exposure to various toxins (chemotherapy agents, radiation treatment, petrochemical toxins) that may put a person at increased risk of developing AML. He also explains the importance of long-term monitoring and explains residual disease versus complete remission.

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Understanding AML-MRC and tAML

Understanding Erythropoiesis

Understanding Erythropoiesis

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Treating AML

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Animation - Treatment Failure and Relapse
Animation - Treatment Failure and Relapse
Slide Show - Treatment Failure and Relapse
Slide Show - Treatment Failure and Relapse
Expert Videos
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1. What is treatment failure and relapse in AML?
Who is at risk of treatment failure and relapse in AML?
2. Who is at risk of treatment failure and relapse in AML?
What happens in treatment failure in AML?
3. What happens in treatment failure in AML?
Why does AML treatment failure happen after chemo and/or radiation therapy?
4. Why does AML treatment failure happen after chemo and/or radiation therapy?
How common is treatment failure and relapse in AML?
5. How common is treatment failure and relapse in AML?
Can AML be cured?
6. Can AML be cured?
How does targeted therapy impact AML remission?
7. How does targeted therapy impact AML remission?
Is remission the same in younger or older patients with AML?
8. Is remission the same in younger or older patients with AML?
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9. How does AML classification help predict treatment outcomes?
Are clinical trials an option in treatment failure or relapse in AML?
10. Are clinical trials an option in treatment failure or relapse in AML?
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Ed's story: What has your AML diagnosis and treatment journey been so far?
11. Ed's story: What has your AML diagnosis and treatment journey been so far?
Ed's story: What has helped you cope on a daily basis with your AML diagnosis?
12. Ed's story: What has helped you cope on a daily basis with your AML diagnosis?
Ed's story: What advice do you have for other patients on their journey with AML?
13. Ed's story: What advice do you have for other patients on their journey with AML?
Paul's story: How was your AML diagnosed and what experiences have you had with treatment?
14. Paul's story: How was your AML diagnosed and what experiences have you had with treatment?
Paul's story: What advice do you have for other patients with AML?
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Peggy's story: How did you first cope with your diagnosis of AML?
17. Peggy's story: How did you first cope with your diagnosis of AML?
Peggy's story: What advice do you have for other AML patients managing treatment side effects?
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This educational activity has been developed by the Myelodysplastic Syndromes Foundation, Inc. and Mechanisms in Medicine Inc.

This activity is supported by educational grants from AbbVie, Acceleron, Bristol-Myers Squibb, Celgene Corporation, Daiichi Sankyo, Jazz Pharmaceuticals and Takeda Oncology.

This website is part of the Animated Patient™ series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.