Expert Video - How do doctors tell de novo AML, AML-MRC, and tAML apart?
Dr. David Steensma, an expert on acute myeloid leukemia (AML), explains that your medical history and cells from a bone marrow biopsy help doctors tell types of AML apart. Chemotherapy or radiation in the last 10 years indicates treatment-related AML (tAML), especially if there is a certain genetic pattern. AML with myelodysplasia-related changes (AML-MRC) has certain cell changes that can be seen under a microscope. Without these changes or prior treatment, it is likely de novo AML. People with de novo AML also tend to have higher white blood cell counts.
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